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Minimally invasive treatment of early gastrointestinal cancer and biliary-pancreatic diseases

Professor Hu Bing’s team of Digestive Endoscopy Center, West China Hospital, Sichuan University, focuses on basic and clinical research of early gastrointestinal cancer and biliary-pancreatic diseases. The team has established a clinical and biological sample database of early gastrointestinal cancer and conducted multi-field and cross-disciplinary researches on a full medical chain in endoscopic field including endoscopic detection, early cancer diagnosis, preoperative evaluation, ESD, pathological characteristics, postoperative follow-up, cancer pathogenesis, epidemiological investigation, technological innovation as well as medical product development, etc. With superb medical skill, innovation, R&D capability as well as professional services, professor Hu’s team is well-renowned both at home and abroad.

In recent years, Professor Hu Bing’s team has made outstanding achievements in the field of minimally invasive treatment for early gastrointestinal cancer and biliary-pancreatic diseases. The team has innovatively created 7 new endoscopic procedures in the world, and obtained 3 independent patents. All these patents are under the process of commercialization now and one patent product has already been on market.

1. O-POEM, namely open peroral endoscopic myotomy. It treats cardia achalasia by directly incision of the mucosa, submucosa and muscularis propria without building a submucosal tunnel.
2.D-POEM, Diverticular POEM, tunneling technique for esophageal diverticulum. After the successful debut in the international conference in 2015, this new procedure is highly praised by medical colleagues at home and abroad, and has now become the first-line treatment for esophageal diverticulum.
3. Dual-POEM, dual peroral endoscopic myotomy. It significantly improves the life quality of patients with achalasia and reduces their financial burden.
4. Post-Cut, post endoscopic sphincterotomy for duodenal papillary. In ERCP, the duodenum papilla is re-opened with a needle knife. It can quickly release the impacted stones under emergent circumstance as a safe and effective method.
5. MAB-ESD, ESD with endoscopic magnetic beads. The gravity and magnetic characteristics of the beads were used for traction and surgical field exposure. This is the first endoscopic traction technique invented by Chinese doctors. Magnetic bead for endoscopic application has obtained state patent.
6. MAD, Magnet-assisted auto diverticuloplasty. As a completely bloodless surgery, this is an innovative model of magnetic compression treatment.
7. Double-PEG, double percutaneous endoscopic gastrostomy. It provides treatment for chronic, refractory duodenal fistula.
8. Plastic anti-reflux Biliary Stent. Traditional plastic biliary stent has a high rate of retrograding infection, which seriously affects patients’ quality of life. The plastic anti-reflux Biliary Stent can reduce the infection rate by 20%. The product has obtained patent and is now under process of commercialization.
9. Biliary spontaneous dislodgement spiral stent (BSDSS). The current methods for ERCP biliary drainage have respective defects. BSDSS developed by the team achieves sufficient drainage without any discomfort or second endoscopy to remove the stent. The stent can also be excreted from the body naturally. The product has obtained patent and is now under process of commercialization.

Until now, doctors from several prestigious hospitals in the USA, including Mayo Clinic, Johns Hopkins and Southwestern Medical Center, have come to the Endoscopic Center of West China Hospital for advanced endoscopic training. Dozens of doctors from Europe, Canada and India also come to study endoscopic skills. In January 2017 and June 2019, professor Hu was invited to give lectures at the Southwestern Medical Center and Johns Hopkins Hospital in the USA. Through technical exchanges and cooperation with European, American countries and those along the Belt and Road, Professor Hu Bing’s team will keep the high ground of innovation technology in the global stage.